Welcome to GALAXY

GALAXY: Gut-and-liver axis in alcoholic liver fibrosis

Exploring the role of the gut microbiome in alcoholic liver fibrosis to improve understanding, diagnosis, prevention and treatment of chronic liver disease.

News

Nov 10, 2016
Posted by: livergalaxy

The GALAXY flyer is now ready for download! Find the folder under activities

The flyer is produced by the GALAXY project management group in coorporation with the University of Southern Denmark. 

Jul 1, 2016
Posted by: livergalaxy

The GALAXY website is launched at the 1st of July. Please contact the project manager, if you have any questions. 

Apr 16, 2016
Posted by: livergalaxy

GALAXY is represented at the International Liver Congress 2016 in Barcelona, Spain.

Coordinator Aleksander Krag will speak at the Session on Securing the fucture of Liver research – Funding and Consortium Strategies – On how GALAXY succecfully obtained EU funding.


GALAXY

GALAXY has the ambition, by combining unique capabilities in European institutions, to perform integrated systems modelling of multi-omics data together with clinical data. To improve understanding of alcoholic liver fibrosis, and to develop diagnostic, prevention and treatment programs.


CONCEPT AND APPROACH

1. The hypothesis of GALAXY is that specific gut microbiome characteristics and associated host gene expression and metabolic changes in alcohol overusing individuals are key determinants for the development and progression of alcoholic liver fibrosis.

2. These key determinants can be used to develop novel biomarkers to detect alcoholic liver fibrosis before advancing into cirrhosis and stratify patients for risk of disease progression.

3. Understanding disease complexity will, in addition to early detection, also be used to develop new treatments to halt liver fibrosis by altering the microbiome.

4. We propose that alcoholic liver fibrosis through a systems medicine approach of well-phenotyped cohorts can be better understood, detected at an earlier stage and disease progression stopped.